@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP976646.RAfdZ0gSWwDFmkd5cfPg9skf3FaYn6RP6VTwM1tThNJpQ> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v3.0.0/void/> .

dgn-np:NP976646.RAfdZ0gSWwDFmkd5cfPg9skf3FaYn6RP6VTwM1tThNJpQ130_head {
  this: np:hasAssertion dgn-np:NP976646.RAfdZ0gSWwDFmkd5cfPg9skf3FaYn6RP6VTwM1tThNJpQ130_assertion;
    np:hasProvenance dgn-np:NP976646.RAfdZ0gSWwDFmkd5cfPg9skf3FaYn6RP6VTwM1tThNJpQ130_provenance;
    np:hasPublicationInfo dgn-np:NP976646.RAfdZ0gSWwDFmkd5cfPg9skf3FaYn6RP6VTwM1tThNJpQ130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP976646.RAfdZ0gSWwDFmkd5cfPg9skf3FaYn6RP6VTwM1tThNJpQ130_assertion a np:Assertion .
  
  dgn-np:NP976646.RAfdZ0gSWwDFmkd5cfPg9skf3FaYn6RP6VTwM1tThNJpQ130_provenance a np:Provenance .
  
  dgn-np:NP976646.RAfdZ0gSWwDFmkd5cfPg9skf3FaYn6RP6VTwM1tThNJpQ130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP976646.RAfdZ0gSWwDFmkd5cfPg9skf3FaYn6RP6VTwM1tThNJpQ130_assertion {
  miriam-gene:157313 a ncit:C16612 .
  
  lld:C0025202 a ncit:C7057 .
  
  dgn-gda:DGN7e601447c5ca9a2098efaffb02cd76d2 sio:SIO_000628 miriam-gene:157313, lld:C0025202;
    a sio:SIO_001121 .
}

dgn-np:NP976646.RAfdZ0gSWwDFmkd5cfPg9skf3FaYn6RP6VTwM1tThNJpQ130_provenance {
  dgn-np:NP976646.RAfdZ0gSWwDFmkd5cfPg9skf3FaYn6RP6VTwM1tThNJpQ130_assertion dcterms:description
      "[Further analysis of expression signatures associated with melanoma progression using functional annotations categorized these transcripts into three classes of genes: 1) Upregulation of activators of cell cycle progression, DNA replication and repair (CDCA2, NCAPH, NCAPG, NCAPG2, PBK, NUSAP1, BIRC5, ESCO2, HELLS, MELK, GINS1, GINS4, RAD54L, TYMS, and DHFR), 2) Loss of genes associated with cellular adhesion and melanocyte differentiation (CDH3, CDH1, c-KIT, PAX3, CITED1/MSG-1, TYR, MELANA, MC1R, and OCA2), 3) Upregulation of genes associated with resistance to apoptosis (BIRC5/survivin).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:17611626;
    prov:wasDerivedFrom dgn-void:befree-20150227;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-20150227 pav:importedOn "2015-02-27"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP976646.RAfdZ0gSWwDFmkd5cfPg9skf3FaYn6RP6VTwM1tThNJpQ130_publicationInfo {
  this: dcterms:created "2015-08-25T14:47:36+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetv3.0rdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v3.0.0.0" .
  
  dgn-void:disgenetv3.0rdf pav:version "v3.0.0" .
}