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[The wild-type HH (HFE) protein complexes with the transferrin receptor (TFR), and two HFE mutations (Cys282Tyr and His63Asp) have been found to increase the affinity of the TFR for transferrin resulting in an increased cellular uptake of iron.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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