@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAeWBFlJ3mH4gB_7rOULe4KpUpeTEue0qnE049ErXGdCs> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAeWBFlJ3mH4gB_7rOULe4KpUpeTEue0qnE049ErXGdCs#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 hasAgent: sub:_2;
    a go:0016301 .
  
  sub:_2 geneProductOf: hgnc:9829;
    a Protein: .
  
  sub:_3 hasAgent: sub:_4;
    a go:0016301 .
  
  sub:_4 geneProductOf: hgnc:2730;
    a Protein: .
  
  sub:_5 hasAgent: sub:_6;
    a go:0016301 .
  
  sub:_6 geneProductOf: hgnc:6871;
    a Protein: .
  
  sub:_7 rdf:object sub:_5;
    rdf:predicate belv:increases;
    rdf:subject sub:_3;
    a rdf:Statement .
  
  sub:_8 occursIn: obo:CLO_0001235, species:9606;
    rdf:object sub:_7;
    rdf:predicate belv:increases;
    rdf:subject sub:_1;
    a rdf:Statement .
  
  sub:assertion rdfs:label "kin(p(HGNC:DDR1)) -> kin(p(HGNC:MAPK1))", "kin(p(HGNC:RAF1)) -> (kin(p(HGNC:DDR1)) -> kin(p(HGNC:MAPK1)))" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_10;
    pav:version "20131211" .
  
  sub:_10 rdfs:label "Selventa" .
  
  sub:_9 prov:value "We further demonstrated that DDR1 activated the MAPK cascade in a Ras-dependent manner. When DDR1 and either a DN mutant form of Ras (N17Ras) or Raf1 (DN-Raf-Flag), a direct downstream effector of Ras, were transiently transfected into 293T cells stimulated with collagen IV, activation levels of ERK were substantially decreased (Figure 4B). These findings demonstrated that DDR1 activates MAPK through Ras and Raf, as has been demonstrated for p53-induced MAPK activation (Lee et al., 2000).";
    prov:wasQuotedFrom pubmed:12628922 .
  
  sub:assertion prov:hadPrimarySource pubmed:12628922;
    prov:wasDerivedFrom beldoc:, sub:_9 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:31:59.837+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}