sub:assertion { d:DB05775v:identifier "DB05775" ; v:namespace "drugbank" ; v:uri "http://bio2rdf.org/drugbank:DB05775" ; v:x-identifiers.org <http://identifiers.org/drugbank/DB05775> ; dv:drugbank-id "DB05775" ; dv:x-cas <http://bio2rdf.org/cas:> ; dct:description "CRx-401 is a novel insulin sensitizer designed to provide anti-diabetic activity without promoting weight gain. It consists of a low dose of the analgesic diflunisal in conjunction with a modified-release therapeutic dose of bezafibrate, an anti-cholesterol agent. In third-party clinical studies, the dose of bezafibrate contained in CRx-401 has been observed to have a positive impact on cellular pathways that influence glycemic and lipid profiles, and this dose has proven to be well tolerated in clinical trials. Unlike other NSAIDs, or non-steroidal anti-inflammatory drugs, the dose of diflunisal in CRx-401 has demonstrated in preclinical studies the ability to synergistically enhance the anti-diabetic effects of bezafibrate through novel disease-targeted mechanisms."@en ; dct:identifier "drugbank:DB05775" ; dct:title "CRx-401"@en ; adv:Drug ; rdfs:label "CRx-401 [drugbank:DB05775]"@en ; rdfs:seeAlso <http://www.drugbank.ca/drugs/DB05775> . }