@prefix dcterms: .
@prefix this: .
@prefix sub: .
@prefix beldoc: .
@prefix rdfs: .
@prefix rdf: .
@prefix xsd: .
@prefix dce: .
@prefix pav: .
@prefix np: .
@prefix belv: .
@prefix prov: .
@prefix Protein: .
@prefix hgnc: .
@prefix geneProductOf: .
@prefix hasPart: .
@prefix ProteinComplex: .
@prefix go: .
@prefix hasAgent: .
@prefix species: .
@prefix occursIn: .
@prefix pubmed: .
@prefix orcid: .
sub:Head {
this: np:hasAssertion sub:assertion;
np:hasProvenance sub:provenance;
np:hasPublicationInfo sub:pubinfo;
a np:Nanopublication .
}
sub:assertion {
sub:_1 hasPart: sub:_2, sub:_3;
a ProteinComplex: .
sub:_2 geneProductOf: hgnc:2348;
a Protein: .
sub:_3 geneProductOf: hgnc:2345;
a Protein: .
sub:_4 hasAgent: sub:_5;
a go:0042789 .
sub:_5 geneProductOf: hgnc:2345;
a Protein: .
sub:_6 occursIn: species:9606;
rdf:object sub:_4;
rdf:predicate belv:directlyIncreases;
rdf:subject sub:_1;
a rdf:Statement .
sub:assertion rdfs:label "complex(p(HGNC:CREBBP),p(HGNC:CREB1)) => tscript(p(HGNC:CREB1))" .
}
sub:provenance {
beldoc: dce:description "Approximately 61,000 statements.";
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
dce:title "BEL Framework Large Corpus Document";
pav:authoredBy sub:_8;
pav:version "20131211" .
sub:_7 prov:value "Moreover, PP1 was shown to act as a major CTD phosphatase in nuclear extracts and to affinity-purify with RNA polymerase II. Both PP1 and the nuclear regulator NIPP1 have also been identified as components of the Tat-associated RNA polymerase II complex, which regulates transcription from the human immunodeficiency virus type 1 promoter (40, 275). The transcription factor CREB mediates the expression of cAMP-induced genes by binding to a conserved cAMP-responsive element. Phosphorylation of CREB on Ser-133, e.g., by PKA, promotes the recruitment of the histone acetyltransferase CBP, which facilitates access of the promoter region to the transcriptional machinery.";
prov:wasQuotedFrom pubmed:14715909 .
sub:_8 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:14715909;
prov:wasDerivedFrom beldoc:, sub:_7 .
}
sub:pubinfo {
this: dcterms:created "2014-07-03T14:32:14.595+02:00"^^xsd:dateTime;
pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}