http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#Head http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#assertion http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#provenance http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#pubinfo http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#assertion http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#_1 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=6014 http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697 http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#_2 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/CL_0000542 http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#_2 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#_1 http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/decreases http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://resource.belframework.org/belframework/20131211/namespace/selventa-legacy-chemicals/Hydrocortisone http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#assertion http://www.w3.org/2000/01/rdf-schema#label a(SCHEM:Hydrocortisone) -| r(HGNC:IL4) http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#_4 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#_3 http://www.w3.org/ns/prov#value Given that glucocorticoids (GCS) were reported to increase the production of interleukin 4 (IL4) by mouse T cells and that GCS are widely used to treat allergic diseases it was important to examine the effect of these agents on IL4 production by human lymphocytes. We here demonstrate that the production of IL4 by human lymphocytes is markedly inhibited by small concentrations of hydrocortisone. The suppression is observed at the protein and at the mRNA levels and it is not secondary to the GCS-induced inhibition of IL2 production. http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/1915563 http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/1915563 http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#_3 http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc#pubinfo http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc http://purl.org/dc/terms/created 2014-07-03T14:33:32.185+02:00 http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAeD9RSHuinVlU_YE383-Tq505yxOWJO4Z4HYP5jwFTDc http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234