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Thus, the free fraction of glisentide may be increased. A dosage reduction may be required if used in combination. http://bio2rdf.org/drugbank_resource:DB01050_DB08814 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://bio2rdf.org/drugbank_vocabulary:Drug-Drug-Interaction http://bio2rdf.org/drugbank_resource:DB01050_DB08814 http://www.w3.org/2000/01/rdf-schema#label DDI between Ibuprofen and Triflusal - The metabolite of triflusal, 2-hydroxy-4-trifluoro-methyl-benzoic acid (HTB), impairs the serum protein binding of ibuprofen to the same extent as acetylsalisylic acid. Thus, the free fraction of glisentide may be increased. A dosage reduction may be required if used in combination. 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