. . . . . . . . . . . . "[The C allele of rs3815148 on chromosome 7q22 (minor allele frequency 23%; intron 12 of the COG5 gene) was associated with a 1.14-fold increased risk (95% confidence interval 1.09-1.19) of knee and/or hand OA (P = 8 x 10(-8)) and also with a 30% increased risk of knee OA progression (95% confidence interval 1.03-1.64) (P = 0.03).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2016-01-27"^^ . . "Gene-disease associations manually curated."@en . "DisGeNET evidence - CURATED"@en . "2016-05-13T12:42:12+02:00"^^ . . . . . . . . . . . "v4.0.0.0" . "v4.0.0" .