http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#Head http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#assertion http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#provenance http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#pubinfo http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#assertion http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_1 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_2 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016301 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=3236 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_3 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_4 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016301 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_4 http://purl.obolibrary.org/obo/RO_0002204 http://resource.belframework.org/belframework/20131211/namespace/selventa-protein-families/MAPK%20Erk1%2F2%20Family http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_5 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/UBERON_0002367 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_5 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_3 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_1 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#assertion http://www.w3.org/2000/01/rdf-schema#label kin(p(HGNC:EGFR)) -> kin(p(SFAM:"MAPK Erk1/2 Family")) http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_7 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_6 http://www.w3.org/ns/prov#value Recent studies from our laboratory [63] have shown that treatment of mammary epithelial cells with Wnt-1 or Wnt-5a activates ErbB1 and the MAPK cascade. The effect is rapid and can be blocked by an ErbB1 mAb that interferes with ligand binding, or by metalloproteinase inhibitors. These results suggest that in a manner similar to that described for GPCR agonists, Wnt binding to Fz transactivates ErbB1 by increasing the availability of an ErbB1 ligand. Interestingly, Wnt-transactivated ErbB1 was responsible for MAPK activation and for the increased levels of cyclin D1 that were found in Wnt-1-expressing cells. http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/12648469 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/12648469 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#_6 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U#pubinfo http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U http://purl.org/dc/terms/created 2014-07-03T14:32:00.296+02:00 http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAdZtgQT3vzHwYIoMmD2maX-35ylh3K4g-rDwn7Yp7D4U http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234