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[The results of DNA analysis of colorectal adenocarcinomas varied greatly depending on study methodology but several important points can be summarized: (1) higher stage tumors have a greater proportion of aneuploid tumors; (2) aneuploid tumors tend to have a higher growth rate (SPF) and poorer survival than diploid tumors; and (3) aneuploid tumors are associated with histological parameters indicative of a poor prognosis such as vascular invasion, but ploidy is not related to tumor grade.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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