sub:assertion { d:DB00382dv:ddi-interactor-indr:DB00382_DB00501 . d:DB00501dv:ddi-interactor-indr:DB00382_DB00501 . dr:DB00382_DB00501dcterms:identifier "drugbank_resource:DB00382_DB00501" ; dcterms:title "DDI between Tacrine and Cimetidine - The metabolism of Tacrine, a CYP1A2 substrate, may be reduced by Cimetidine, a CYP1A2 inhibitors. Monitor the efficacy and toxicity of Tacrine if Cimetidine is initiated, discontinued or if the dose is changed."@en ; adv:Drug-Drug-Interaction ; rdfs:label "DDI between Tacrine and Cimetidine - The metabolism of Tacrine, a CYP1A2 substrate, may be reduced by Cimetidine, a CYP1A2 inhibitors. Monitor the efficacy and toxicity of Tacrine if Cimetidine is initiated, discontinued or if the dose is changed. [drugbank_resource:DB00382_DB00501]"@en . }