http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ130_head http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ130_assertion http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ130_provenance http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ130_publicationInfo http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ130_assertion http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Assertion http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ130_provenance http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Provenance http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ130_publicationInfo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#PublicationInfo http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ130_assertion http://identifiers.org/ncbigene/3845 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16612 http://linkedlifedata.com/resource/umls/id/C0009402 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7057 http://rdf.disgenet.org/resource/gda/DGN1c612637d9b8d99f2bd4307c4023c550 http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/3845 http://rdf.disgenet.org/resource/gda/DGN1c612637d9b8d99f2bd4307c4023c550 http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C0009402 http://rdf.disgenet.org/resource/gda/DGN1c612637d9b8d99f2bd4307c4023c550 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001121 http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ130_provenance http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ130_assertion http://purl.org/dc/terms/description [In search of effective combination therapies, we show here that simultaneous targeting of EGFR with its inhibitor, erlotinib and mTOR with its inhibitor, rapamycin inhibits the phosphorylation and activation of downstream phosphatidylinositol 3-kinase (PI3K), Akt, mTOR and extracellular-signal-regulated kinase 1/2 (Erk1/2) pathways, resulting in the inhibition of cell cycle progression and the growth of both KRAS wild-type and mutated colorectal carcinoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ130_assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v4.0.0/void/source_evidence_literature http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ130_assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/22552366 http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ130_assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v4.0.0/void/befree-2016 http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ130_assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/ECO_0000203 http://rdf.disgenet.org/v4.0.0/void/befree-2016 http://purl.org/pav/importedOn 2016-02-19 http://rdf.disgenet.org/v4.0.0/void/source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/ECO_0000212 http://rdf.disgenet.org/v4.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v4.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ130_publicationInfo http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ http://purl.org/dc/terms/created 2016-05-13T12:49:08+02:00 http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v4.0.0/void/IBIGroup http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v4.0.0/void/disgenetv3.0rdf http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ http://purl.org/pav/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ http://purl.org/pav/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ http://purl.org/pav/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ http://purl.org/pav/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ http://purl.org/pav/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ http://purl.org/pav/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP979133.RAdCUyf0fTahN3ONpGcfD0AFhZaU2VrSazHlUGtHWKcaQ http://purl.org/pav/version v4.0.0.0 http://rdf.disgenet.org/v4.0.0/void/disgenetv3.0rdf http://purl.org/pav/version v4.0.0