sub:provenance {
beldoc: dce:description "Approximately 61,000 statements." ;
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title "BEL Framework Large Corpus Document" ;
pav:authoredBy sub:_6 ;
pav:version "20131211" .
sub:_5 prov:value "Finally, we show that retroviral T-bet expression in developing and established Th2 cells leads to down-regulation of GATA-3 levels. (from text): As shown in Fig. 5 E, although GATA-3 mRNA levels in untreated T-bet–expressing D10 cells were suppressed to about half of the level found in the wild-type cells, the kinetics of degradation of GATA-3 mRNA was similar in T-bet–expressing and nonexpressing D10 cells. These results suggest that T-bet suppresses GATA-3 at a transcriptional level rather than at a posttranscriptional level. However, it should be noted that some posttranslational control may also exist because the down-regulation of GATA-3 by T-bet is more evident at the protein level than it is at the mRNA level." ;
prov:wasQuotedFrom pubmed:16520391 .
sub:_6 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:16520391 ;
prov:wasDerivedFrom beldoc: ,
sub:_5 .
}