. . . . . . . . . . . . . . "p(HGNC:TP63) => r(HGNC:MFGE8)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "{Modeled as TP63 and not taof because the 'dominant negative' TP63 lacking a transcriptional activation domain also activates the gene - SE} We determined that the trans-activator (TA) isoforms of p63 activate MFGE8 transcription though a p53/p63 motif at -370, which was confirmed by a chromatin immunoprecipitation experiment. Upon siRNA-mediated p63 silencing in a squamous cell carcinoma line, MFG-E8 production decreased to diminish Saos-2 cell adhesion. Interestingly, the DeltaN-p63 isoform lacking the TA domain enhanced the MFGE8-activating function of TA-p63" . . "Selventa" . . . . "2014-07-03T14:33:11.961+02:00"^^ . . .