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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAcJsingHO2Q5dWFJ-G5D7SGu0EyewAbMKzaKaE7dZNBs#_3 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAcJsingHO2Q5dWFJ-G5D7SGu0EyewAbMKzaKaE7dZNBs#_2 http://www.w3.org/ns/prov#value cAMP and cGMP reduce [Ca2]i and relax smooth muscle through their cAMP- (PKA) and cGMP-activated (PKG) kinases (50, 410, 418). Several effects of cAMP are mediated by cross activation of PKG (50, 104), and significant components of the relaxant effects of cGMP are mediated through Ca2 desensitization (188) (Fig. 6). 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