http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w130_head http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w130_assertion http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w130_provenance http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w130_publicationInfo http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w130_assertion http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Assertion http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w130_provenance http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Provenance http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w130_publicationInfo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#PublicationInfo http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w130_assertion http://identifiers.org/ncbigene/207 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16612 http://linkedlifedata.com/resource/umls/id/C0005684 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7057 http://rdf.disgenet.org/resource/gda/DGNf4fb63db067a82c82f2d994272dc2c40 http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/207 http://rdf.disgenet.org/resource/gda/DGNf4fb63db067a82c82f2d994272dc2c40 http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C0005684 http://rdf.disgenet.org/resource/gda/DGNf4fb63db067a82c82f2d994272dc2c40 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001121 http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w130_provenance http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w130_assertion http://purl.org/dc/terms/description [Manipulating the expression of mutant or wild-type PIK3CA or DUSP1 confirmed that this mechanism is responsible for the induction of apoptosis and the inhibition of tumour proliferation in vitro and in vivo, to sensitise cells to AKT target therapy.Conclusion or interpretation:PIK3CA mutations confer sensitivity to AKT target therapy in BLCA by regulating DUSP1 expression and subsequent ERK1/2 dephosphorylation and can potentially serve as a stratifying biomarker for treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w130_assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w130_assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/25349966 http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w130_assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v3.0.0/void/befree-20150227 http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w130_assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/ECO_0000203 http://rdf.disgenet.org/v3.0.0/void/befree-20150227 http://purl.org/pav/importedOn 2015-02-27 http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/ECO_0000212 http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w130_publicationInfo http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w http://purl.org/dc/terms/created 2015-08-25T14:39:52+02:00 http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v3.0.0/void/IBIGroup http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v3.0.0/void/disgenetv3.0rdf http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w http://purl.org/pav/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w http://purl.org/pav/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w http://purl.org/pav/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w http://purl.org/pav/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w http://purl.org/pav/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w http://purl.org/pav/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP231832.RAcA2zFIvsCIu_NNeQ75G1Z-5-kmnx1bkL69Kyjwcgl7w http://purl.org/pav/version v3.0.0.0 http://rdf.disgenet.org/v3.0.0/void/disgenetv3.0rdf http://purl.org/pav/version v3.0.0