. . . . . . . . . . . . . . . . . "kin(complex(SCOMP:\"p85/p110 PI3Kinase Complex\")) -> kin(p(HGNC:PDPK1))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "Figure 2. A schematic diagram shows the cellular signalling pathway by which ENaC is regulated by the hormones aldosterone and insulin. The effect of aldosterone and insulin is mediated via a phosphatidylinositol 3-kinase (PI3K) and phosphoinositide-dependent protein kinase (PDK) pathway, which activates serum and glucocorticoid-dependent protein kinase (Sgk1) and protein kinase B (Akt1). Both Sgk1 and Akt1 phosphorylate Nedd4-2. The phosphorylated form of Nedd4-2 interacts with 14-3-3, preventing it from binding to and inducing ubiquitination of ENaC. " . . "Selventa" . . . . "2014-07-03T14:33:15.808+02:00"^^ . . .