sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_6 ; pav:version "20131211" . sub:_5prov:value "In these experiments p53â??223Leu was as active as wild-type p53 in transactivation of the reporter construct, whereas p53â??274Phe had no detectable activity (Fig. 4b). Coexpression of p53â??274Phe inhibited transactivation by p53â??223Leu, thus correlating with the above-described effects of this mutant on growth-inhibitory activity of p53â??223Leu. The lack of detectable transactivation activity of p53â??274Phe suggests that the toxicity of this protein to 10(1) cells is mediated not through p21." ; prov:wasQuotedFrompubmed:12782597 . sub:_6rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:12782597 ; prov:wasDerivedFrombeldoc: , sub:_5 . }