@prefix this: <http://rdf.disgenet.org/nanopublications.trig#NP614148.RAbw1GxR29j0zka7-Ynw0woQPxxxHW13t_zZuZe43lMhI> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/eco.owl#> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/2.0/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/nanopublications.trig#> .
@prefix dgn-gda: <http://rdf.disgenet.org/gene-disease-association.ttl#> .
@prefix dgn-void: <http://rdf.disgenet.org/v2.1.0/void.ttl#> .

dgn-np:NP614148.RAbw1GxR29j0zka7-Ynw0woQPxxxHW13t_zZuZe43lMhI130_head {
  this: np:hasAssertion dgn-np:NP614148.RAbw1GxR29j0zka7-Ynw0woQPxxxHW13t_zZuZe43lMhI130_assertion;
    np:hasProvenance dgn-np:NP614148.RAbw1GxR29j0zka7-Ynw0woQPxxxHW13t_zZuZe43lMhI130_provenance;
    np:hasPublicationInfo dgn-np:NP614148.RAbw1GxR29j0zka7-Ynw0woQPxxxHW13t_zZuZe43lMhI130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP614148.RAbw1GxR29j0zka7-Ynw0woQPxxxHW13t_zZuZe43lMhI130_assertion a np:Assertion .
  
  dgn-np:NP614148.RAbw1GxR29j0zka7-Ynw0woQPxxxHW13t_zZuZe43lMhI130_provenance a np:Provenance .
  
  dgn-np:NP614148.RAbw1GxR29j0zka7-Ynw0woQPxxxHW13t_zZuZe43lMhI130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP614148.RAbw1GxR29j0zka7-Ynw0woQPxxxHW13t_zZuZe43lMhI130_assertion {
  miriam-gene:1280 a ncit:C16612 .
  
  lld:C0596263 a ncit:C7057 .
  
  dgn-gda:DGNbd1df5a30fc2804f9c2d77cda2c41a4a sio:SIO_000628 miriam-gene:1280, lld:C0596263;
    a sio:SIO_001121 .
}

dgn-np:NP614148.RAbw1GxR29j0zka7-Ynw0woQPxxxHW13t_zZuZe43lMhI130_provenance {
  dgn-np:NP614148.RAbw1GxR29j0zka7-Ynw0woQPxxxHW13t_zZuZe43lMhI130_assertion dcterms:description
      "[Taken together, our results demonstrate that 1) expression of PKCbetaII in the colonic epithelium is both necessary and sufficient to confer susceptibility to AOM-induced colon carcinogenesis in transgenic mice, 2) PKCbetaII regulates its own expression in RIE and human colon cancer cells in vitro and in the colonic epithelium in vivo, and 3) PKCbetaII autoregulation is mediated through a MEK-dependent signaling pathway in RIE/PKCbetaII and HCT116 colon cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:15322124;
    prov:wasDerivedFrom dgn-void:befree-20140225;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP614148.RAbw1GxR29j0zka7-Ynw0woQPxxxHW13t_zZuZe43lMhI130_publicationInfo {
  this: dcterms:created "2014-10-02T12:38:11+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetrdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v2.1.0.0" .
  
  dgn-void:disgenetrdf pav:version "v2.1.0" .
}