. . . . . . . . . . . . . . . . . . "bp(GOBP:\"response to hypoxia\") -> p(SFAM:\"HSP90 Family\")" . "kin(complex(SCOMP:\"p85/p110 PI3Kinase Complex\")) -> (bp(GOBP:\"response to hypoxia\") -> p(SFAM:\"HSP90 Family\"))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "Considering that PI3K inhibitors down-regulated heat shock protein 90 (Hsp90) as well as Hsp70 expression and moreover attenuated heat- or hypoxia-induced Hsp70 as well as hypoxia-induced Hsp90 up-regulation we conclude that PI3K inhibition promoted degradation of HIF-1alpha indirectly by reducing steady state concentrations of Hsp90 and/or Hsp70." . . "Selventa" . . . . "2014-07-03T14:32:15.021+02:00"^^ . . .