. . . . . . . . . . . . . . "p(MGI:Htt) -> r(MGI:Cdkn1c)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "(from text) We confirmed this essential role for huntingtin on our arrays, detecting the general down-regulation of genes involved in growth, proliferation and cellular differentiation (Fig. 6). A subset of these transcripts appear to function specifically within the brain: Serpinf1, Emp3, Tcfap2c, Dlx3 and Elavl4. Many general growth-related or mitogenic mRNAs (Ghrh, Scgb3a1, Cdkn1c, Sp6, Gkn1, Igf2) also exhibited reduced expression. Conversely, Hdh null neurons consistently overexpressed Ccng2, a negative regulator of cell proliferation and cell cycle progression." . . "Selventa" . . . . "2014-07-03T14:33:07.710+02:00"^^ . . .