http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#Head http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#assertion http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#provenance http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#pubinfo http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#assertion http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_1 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=5438 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_2 http://www.selventa.com/vocabulary/translocationFrom http://amigo.geneontology.org/amigo/term/GO:0005622 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_2 http://www.selventa.com/vocabulary/translocationOf http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_3 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_2 http://www.selventa.com/vocabulary/translocationTo http://amigo.geneontology.org/amigo/term/GO:0005576 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_3 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=2545 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_4 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/CL_0000115 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_4 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/UBERON_0004535 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_4 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_2 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_1 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#assertion http://www.w3.org/2000/01/rdf-schema#label p(HGNC:IFNG) -> sec(p(HGNC:CTSS)) http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_6 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_5 http://www.w3.org/ns/prov#value Primary cultured human saphenous vein ECs had negligible levels of Cat S mRNA. Exposure to IFNG, IL-1A, or TNF-A caused accumulation of Cat S transcript. However, the angiogenic factors VEGF and bFGF had limited effects on Cat S transcription (Figure 1A). For detection of Cat S protein in ECs, [125I]JPM ethyl ester, the cell-permeable active site probe for cysteine proteases, was used (Figures 1B and 1C). This irreversible probe labels Cat S immediately on activation and does not affect Cat S immunoreactivity.8 IFNG increased EC secretion of active Cat S 20-fold (mean of three independent experiments by densitometry measurement; Figure 1B, left). Cell-associated Cat S increased in parallel (Figure 1C). VEGF and bFGF also induced Cat S secretion up to 20- and 3-fold, respectively (mean of three independent experiments; Figure 1B, right). http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_5 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/12600886 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_6 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/12600886 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#_5 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc#pubinfo http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc http://purl.org/dc/terms/created 2014-07-03T14:31:59.414+02:00 http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAblCe2wuIxq3U3VkK75pm_wI7zlZ03z_80zsHlH5G-Lc http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234