@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAbLOI3R2gNEQALEXKW6br1-B69tphFb1cuGqXcHeolWQ> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAbLOI3R2gNEQALEXKW6br1-B69tphFb1cuGqXcHeolWQ#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix mesh: <http://purl.bioontology.org/ontology/MSH/> .
@prefix sdis: <http://resource.belframework.org/belframework/20131211/namespace/selventa-legacy-diseases/> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 occursIn: obo:UBERON_0002113, species:9606;
    rdf:object sdis:nephropathy;
    rdf:predicate belv:increases;
    rdf:subject mesh:D006973;
    a rdf:Statement .
  
  sub:assertion rdfs:label "path(MESHD:Hypertension) -> path(SDIS:nephropathy)" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_4;
    pav:version "20131211" .
  
  sub:_2 dce:identifier "C. A. O'Callaghan, Barry M. Brenner";
    dce:title "C. A. O'Callaghan, Barry M. Brenner";
    dce:type "Other" .
  
  sub:_3 prov:value "The primary insult is damage to the renal vessels from the raised pressure. In the interlobular artery walls, muscle is replaced by sclerotic tissue. The afferent arteriole walls undergo hyalinization - the subintimal deposition of lipids and glycoproteins exuded from plasma. Damage to these resistance vessels exposes the glomerular capillary endothelium to hypertension. This reduces glomerular blood flow and filtration, and promotes proteinuria. Inflammatory proteins are exuded from the plasma and ultimately there is glomerular sclerosis or ischemic atrophy.";
    prov:wasQuotedFrom sub:_2 .
  
  sub:_4 rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource sub:_2;
    prov:wasDerivedFrom beldoc:, sub:_3 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:31:29.307+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}