. . . . . . . . . . . . "[The CPE model had been considered but rejected by Penrose, who preferred models postulating changes with age assuming either a power function X10, where X is age or a Poisson model in which accumulation of 17 events was the assumed threshold for the occurrence of Down's syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2014-02-25"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2014-10-02T12:36:03+02:00"^^ . . . . . . . . . . . "v2.1.0.0" . "v2.1.0" .