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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAbDcKlAWL0_712e9WdicOvrCtzWTfkPv2cuTOxNRmzVc#_7 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAbDcKlAWL0_712e9WdicOvrCtzWTfkPv2cuTOxNRmzVc#_6 http://www.w3.org/ns/prov#value Moreover, protein-DNA array studies identified two novel GSK-3-regulated transcription factors, early growth response 1 and Smad3/4, which were oppositely affected by GSK-3alpha or GSK-3beta silencing or inhibition Binding activity of EGR-1-responsive element with EGR-1 was down-regulated by transfection with siRNA for GSK-3{alpha} but up-regulated by siRNA for GSK-3beta compared with the non-targeting siRNA control. 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