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http://www.informatics.jax.org/marker/MGI:108420
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http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
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http://purl.obolibrary.org/obo/BFO_0000066
http://disease-ontology.org/term/DOID:162
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a(CHEBI:lipopolysaccharide) -> a(CHEBI:"reactive oxygen species")
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p(MGI:Nfe2l2) -| (a(CHEBI:lipopolysaccharide) -> a(CHEBI:"reactive oxygen species"))
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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BEL Framework Large Corpus Document
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Thimmulappa et al. (2006b) determined that CDDO-Im protects from deregulation of LPS-induced innate immune response in a Nrf2- dependent manner. Increased NADPH oxidase-dependent ROS generation and pro-inflammatory cytokine (TNF-? and IL-6), and chemokine (MIP2 and MCP-1) production were found in LPS-stimulated peritoneal neutrophils from Nrf2?/? mice relative to cells from Nrf2+/+ mice.
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Selventa
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2014-07-03T14:33:36.032+02:00
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