http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg#head http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg http://www.nanopub.org/nschema#hasAssertion http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg#assertion http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg http://www.nanopub.org/nschema#hasProvenance http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg#provenance http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg http://www.nanopub.org/nschema#hasPublicationInfo http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg#publicationInfo http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg#assertion http://bio2rdf.org/drugbank:DB00395 http://bio2rdf.org/drugbank_vocabulary:ddi-interactor-in http://bio2rdf.org/drugbank_resource:DB00395_DB00745 http://bio2rdf.org/drugbank:DB00745 http://bio2rdf.org/drugbank_vocabulary:ddi-interactor-in http://bio2rdf.org/drugbank_resource:DB00395_DB00745 http://bio2rdf.org/drugbank_resource:DB00395_DB00745 http://purl.org/dc/terms/identifier drugbank_resource:DB00395_DB00745 http://bio2rdf.org/drugbank_resource:DB00395_DB00745 http://purl.org/dc/terms/title DDI between Carisoprodol and Modafinil - Strong CYP2C19 inhibitors such as modafinil may decrease the metabolism of CYP2C19 substrates such as carisoprodol. Consider an alternative for one of the interacting drugs in order to avoid toxicity of the substrate. Some combinations are specifically contraindicated by manufacturers. Suggested dosage adjustments are also offered by some manufacturers. Please review applicable package inserts. Monitor for increased effects of the CYP substrate if a CYP inhibitor is initiated/dose increased, and decreased effects if a CYP inhibitor is discontinued/dose decreased. http://bio2rdf.org/drugbank_resource:DB00395_DB00745 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://bio2rdf.org/drugbank_vocabulary:Drug-Drug-Interaction http://bio2rdf.org/drugbank_resource:DB00395_DB00745 http://www.w3.org/2000/01/rdf-schema#label DDI between Carisoprodol and Modafinil - Strong CYP2C19 inhibitors such as modafinil may decrease the metabolism of CYP2C19 substrates such as carisoprodol. Consider an alternative for one of the interacting drugs in order to avoid toxicity of the substrate. Some combinations are specifically contraindicated by manufacturers. Suggested dosage adjustments are also offered by some manufacturers. Please review applicable package inserts. Monitor for increased effects of the CYP substrate if a CYP inhibitor is initiated/dose increased, and decreased effects if a CYP inhibitor is discontinued/dose decreased. [drugbank_resource:DB00395_DB00745] http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg#provenance http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg#assertion http://semanticscience.org/resource/SIO_000253 http://bio2rdf.org/drugbank_resource:bio2rdf.dataset.drugbank.R3 http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg#publicationInfo http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg#signature.MC0CFAiOtHMTEZE4 http://purl.org/nanopub/x/hasPublicKey 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 http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg#signature.MC0CFAiOtHMTEZE4 http://purl.org/nanopub/x/hasSignature MC0CFAiOtHMTEZE4q67iqt94fQfv+pXmAhUAh7dgfu6UJy8xNTHrVhob0oM3dXY= http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg#signature.MC0CFAiOtHMTEZE4 http://purl.org/nanopub/x/signedBy https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg http://purl.org/dc/terms/created 2018-03-30T11:12:53.666+02:00 http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg http://purl.org/dc/terms/license https://creativecommons.org/licenses/by-nc/4.0/ http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg http://purl.org/nanopub/x/hasSignatureElement http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg#signature.MC0CFAiOtHMTEZE4 http://bio2rdf.org/drugbank_resource:DB00395_DB00745_nanopub.RAapkg64K2J1KuLN1PuTpYEjnr6UCjIndG3NbRnwkXHOg http://www.w3.org/ns/prov#wasGeneratedBy https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.3c184e6c-ceb8-4275-a679-71dfbdac2a11 https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB http://www.w3.org/ns/prov#specializationOf https://github.com/tkuhn/bio2rdf2nanopub https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB http://www.w3.org/ns/prov#wasAttributedTo http://orcid.org/0000-0002-1267-0234 https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.3c184e6c-ceb8-4275-a679-71dfbdac2a11 http://purl.org/dc/terms/identifier 3c184e6c-ceb8-4275-a679-71dfbdac2a11 https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.3c184e6c-ceb8-4275-a679-71dfbdac2a11 http://www.w3.org/ns/prov#used https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349 https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.3c184e6c-ceb8-4275-a679-71dfbdac2a11 http://www.w3.org/ns/prov#wasAssociatedWith https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.3c184e6c-ceb8-4275-a679-71dfbdac2a11 http://www.w3.org/ns/prov#wasStartedBy http://orcid.org/0000-0002-1267-0234 https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349 http://purl.org/dc/terms/isVersionOf https://github.com/tkuhn/bio2rdf2nanopub https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349 http://purl.org/pav/version eda7951a5f6c622c5d2132f50c3093138484a349 https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349 http://www.w3.org/ns/prov#wasAttributedTo http://orcid.org/0000-0002-1267-0234