. . . . . . . "[This study has provided novel information about the structural requirements for the normal function of PCSK9/, more studies are needed to determine the mechanisms by which gain-of-function mutations in PCSK9 cause hypercholesterolemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2009-03-31"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:19:12+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .