@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP1235876.RAaaI9jwOTPHgeHexPpSPVgSCX7e2IyLBRh9mmmocDr4M130_head { this: np:hasAssertion dgn-np:NP1235876.RAaaI9jwOTPHgeHexPpSPVgSCX7e2IyLBRh9mmmocDr4M130_assertion; np:hasProvenance dgn-np:NP1235876.RAaaI9jwOTPHgeHexPpSPVgSCX7e2IyLBRh9mmmocDr4M130_provenance; np:hasPublicationInfo dgn-np:NP1235876.RAaaI9jwOTPHgeHexPpSPVgSCX7e2IyLBRh9mmmocDr4M130_publicationInfo; a np:Nanopublication . dgn-np:NP1235876.RAaaI9jwOTPHgeHexPpSPVgSCX7e2IyLBRh9mmmocDr4M130_assertion a np:Assertion . dgn-np:NP1235876.RAaaI9jwOTPHgeHexPpSPVgSCX7e2IyLBRh9mmmocDr4M130_provenance a np:Provenance . dgn-np:NP1235876.RAaaI9jwOTPHgeHexPpSPVgSCX7e2IyLBRh9mmmocDr4M130_publicationInfo a np:PublicationInfo . } dgn-np:NP1235876.RAaaI9jwOTPHgeHexPpSPVgSCX7e2IyLBRh9mmmocDr4M130_assertion { miriam-gene:406979 a ncit:C16612 . lld:C0009402 a ncit:C7057 . dgn-gda:DGN3ea68d958fe8e24812ea458ef78f849f sio:SIO_000628 miriam-gene:406979, lld:C0009402; a sio:SIO_001121 . } dgn-np:NP1235876.RAaaI9jwOTPHgeHexPpSPVgSCX7e2IyLBRh9mmmocDr4M130_provenance { dgn-np:NP1235876.RAaaI9jwOTPHgeHexPpSPVgSCX7e2IyLBRh9mmmocDr4M130_assertion dcterms:description "[In colorectal cancer samples and corresponding normal colorectal mucosa, miR-18a displayed lower overall expression than other miR-17-92 cluster members. miR-18a was shown to have an opposing role to other miR-17-92 cluster members, in particular the key oncogenic miRNAs, miR-19a and b. Transfection of HCT116 and LIM1215 colorectal cancer cell lines with miR-18a mimics decreased proliferation, while a miR-18a inhibitor increased proliferation. miR-18a was also responsible for decreasing cell migration, altering cell morphology, inducing G1/S phase cell cycle arrest, increasing apoptosis, and enhancing the action of a pro-apoptotic agent.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:25379703; prov:wasDerivedFrom dgn-void:befree-2016; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP1235876.RAaaI9jwOTPHgeHexPpSPVgSCX7e2IyLBRh9mmmocDr4M130_publicationInfo { this: dcterms:created "2016-05-13T12:51:06+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetv3.0rdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v4.0.0.0" . dgn-void:disgenetv3.0rdf pav:version "v4.0.0" . }