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[The aim of our study was to investigate whether common polymorphisms in the genes regulating the early insulin signalling pathway (insulin; A-23T, insulin-like growth factor 1 receptor IGF-1R; GAG1013GAA, plasma cell membrane glycoprotein 1 PC-1; K121Q, insulin receptor substrate IRS-1; G972R, insulin receptor substrate 2 IRS-2; G1057D and phosphatidylinositol 3-kinase p85 alpha PI3K; M326I) affect the weight change and development of Type 2 diabetes in the Finnish Diabetes Prevention Study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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