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[In addition, we identified several `pathway` genes that are rapidly emerging as novel therapeutic targets in cancer (eg, cytosolic phospholipase A2, an upstream target of the cyclooxygenase pathway, and ribosomal protein S6 kinase and eukaryotic translation initiation factor 4E, two important downstream mediators of the mitogenic Akt/mTOR signaling pathway).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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