@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP1201641.RAa4cLAZHAQiugt6wkH8R60PwkSzP1iqS5vUa6B2_ZLX0> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v4.0.0/void/> .

dgn-np:NP1201641.RAa4cLAZHAQiugt6wkH8R60PwkSzP1iqS5vUa6B2_ZLX0130_head {
  this: np:hasAssertion dgn-np:NP1201641.RAa4cLAZHAQiugt6wkH8R60PwkSzP1iqS5vUa6B2_ZLX0130_assertion;
    np:hasProvenance dgn-np:NP1201641.RAa4cLAZHAQiugt6wkH8R60PwkSzP1iqS5vUa6B2_ZLX0130_provenance;
    np:hasPublicationInfo dgn-np:NP1201641.RAa4cLAZHAQiugt6wkH8R60PwkSzP1iqS5vUa6B2_ZLX0130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP1201641.RAa4cLAZHAQiugt6wkH8R60PwkSzP1iqS5vUa6B2_ZLX0130_assertion a np:Assertion .
  
  dgn-np:NP1201641.RAa4cLAZHAQiugt6wkH8R60PwkSzP1iqS5vUa6B2_ZLX0130_provenance a np:Provenance .
  
  dgn-np:NP1201641.RAa4cLAZHAQiugt6wkH8R60PwkSzP1iqS5vUa6B2_ZLX0130_publicationInfo
    a np:PublicationInfo .
}

dgn-np:NP1201641.RAa4cLAZHAQiugt6wkH8R60PwkSzP1iqS5vUa6B2_ZLX0130_assertion {
  miriam-gene:8600 a ncit:C16612 .
  
  lld:C0003873 a ncit:C7057 .
  
  dgn-gda:DGNc36e5851f3835fa928ff6277a5fc59f8 sio:SIO_000628 miriam-gene:8600, lld:C0003873;
    a sio:SIO_001121 .
}

dgn-np:NP1201641.RAa4cLAZHAQiugt6wkH8R60PwkSzP1iqS5vUa6B2_ZLX0130_provenance {
  dgn-np:NP1201641.RAa4cLAZHAQiugt6wkH8R60PwkSzP1iqS5vUa6B2_ZLX0130_assertion dcterms:description
      "[The combination of cytokines present in the circulation of patients with active rheumatoid arthritis might contribute to the generalized bone loss that commonly occurs in these patients, by directly inhibiting osteoblast proliferation and differentiation, but especially by enhancing endogenous cytokine (i.e., receptor activator of nuclear factor-kappa B ligand (RANKL) and interleukin-6 (IL)-6) production by osteoblasts, thereby stimulating osteoclastogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:25027107;
    prov:wasDerivedFrom dgn-void:befree-2016;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP1201641.RAa4cLAZHAQiugt6wkH8R60PwkSzP1iqS5vUa6B2_ZLX0130_publicationInfo {
  this: dcterms:created "2016-05-13T12:50:50+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetv3.0rdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v4.0.0.0" .
  
  dgn-void:disgenetv3.0rdf pav:version "v4.0.0" .
}