@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP381842.RA_wvauaVG2CP12tImbZNDzKl8hACcfNfxxUXpc3YchBA> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v4.0.0/void/> .

dgn-np:NP381842.RA_wvauaVG2CP12tImbZNDzKl8hACcfNfxxUXpc3YchBA130_head {
  this: np:hasAssertion dgn-np:NP381842.RA_wvauaVG2CP12tImbZNDzKl8hACcfNfxxUXpc3YchBA130_assertion;
    np:hasProvenance dgn-np:NP381842.RA_wvauaVG2CP12tImbZNDzKl8hACcfNfxxUXpc3YchBA130_provenance;
    np:hasPublicationInfo dgn-np:NP381842.RA_wvauaVG2CP12tImbZNDzKl8hACcfNfxxUXpc3YchBA130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP381842.RA_wvauaVG2CP12tImbZNDzKl8hACcfNfxxUXpc3YchBA130_assertion a np:Assertion .
  
  dgn-np:NP381842.RA_wvauaVG2CP12tImbZNDzKl8hACcfNfxxUXpc3YchBA130_provenance a np:Provenance .
  
  dgn-np:NP381842.RA_wvauaVG2CP12tImbZNDzKl8hACcfNfxxUXpc3YchBA130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP381842.RA_wvauaVG2CP12tImbZNDzKl8hACcfNfxxUXpc3YchBA130_assertion {
  miriam-gene:3630 a ncit:C16612 .
  
  lld:C0011849 a ncit:C7057 .
  
  dgn-gda:DGNe4892424cce1686590b61a4ce74da62b sio:SIO_000628 miriam-gene:3630, lld:C0011849;
    a sio:SIO_001121 .
}

dgn-np:NP381842.RA_wvauaVG2CP12tImbZNDzKl8hACcfNfxxUXpc3YchBA130_provenance {
  dgn-np:NP381842.RA_wvauaVG2CP12tImbZNDzKl8hACcfNfxxUXpc3YchBA130_assertion dcterms:description
      "[This review focuses on the recent advances in gene therapy of insulin-requiring diabetes, with particular emphasis on 1. the gene delivery systems by viral vectors, since most gene therapy approaches for DM involve the use of viral vectors, paying special attention to current efforts to overcome the disadvantages of adenovirus, adenovirus-associated virus and retrovirus vectors and targeting gene delivery for optimal efficiency of gene expression; 2. coupling the synthesis and release of the transgene insulin to serum glucose concentrations, especially with reference to the current promoters controlling at transcriptional level the ectopic insulin expression in autologous hepatocytes; 3. beta-cell replacement strategies: engineering of beta-cells, especially those derived from pluripotent stem cells, non beta-cells, and on a new comer, the K cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:12553537;
    prov:wasDerivedFrom dgn-void:befree-2016;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP381842.RA_wvauaVG2CP12tImbZNDzKl8hACcfNfxxUXpc3YchBA130_publicationInfo {
  this: dcterms:created "2016-05-13T12:44:38+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetv3.0rdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v4.0.0.0" .
  
  dgn-void:disgenetv3.0rdf pav:version "v4.0.0" .
}