@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RA_n-xNincw0oX3igvgy8XsX_qz6wJ0SJxvqQykz2Wo5Q
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RA_n-xNincw0oX3igvgy8XsX_qz6wJ0SJxvqQykz2Wo5Q#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix chebi: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=
> .
@prefix Protein: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
> .
@prefix hgnc: <
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix atcc: <
http://www.lgcstandards-atcc.org/Products/All/
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix mesh: <
http://purl.bioontology.org/ontology/MSH/
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
sub:_1
geneProductOf:
hgnc:1582
;
a
Protein:
.
sub:_2
occursIn:
mesh:D008168
,
atcc:CRL-5889.aspx
,
species:9606
;
rdf:object
sub:_1
;
rdf:predicate
belv:increases
;
rdf:subject
chebi:18723
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"a(CHEBI:nicotine) -> p(HGNC:CCND1)" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_4
;
pav:version
"1.4" .
sub:_3
prov:value
"Nicotine or NNK (100 nM) increased proliferation ~2-fold in both cell lines. Immunoblotting analysis revealed that after daily administration of nicotine or NNK, Akt activation increased 41.5- fold in both cell lines. The reasons for the less robust increase in Akt activation on day 3 is unclear, but might be related to the higher dose (10 mM) or longer time course (5 days) used in Figure 4A. Increased NSCLC cell proliferation was associated with increased cyclin D1 expression" ;
prov:wasQuotedFrom
pubmed:15790591
.
sub:_4
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:15790591
;
prov:wasDerivedFrom
beldoc:
,
sub:_3
.
}
sub:pubinfo
{
this:
dct:created
"2014-07-03T14:30:33.603+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}