[The 2001 World Health Organization (WHO) classification of myeloid malignancies included these MPDs under the broader category of chronic myeloproliferative diseases (CMPD), which also included chronic neutrophilic leukemia, chronic eosinophilic leukemia/hypereosinophilic syndrome (CEL/HES), and CMPD, unclassifiable. The revised 2008 WHO classification system featured the following changes: 1) the term CMPD was replaced by myeloproliferative neoplasm (MPN), 2) mast cell disease was formally included under the category of MPN, and 3) the subcategory of CEL/HES was reorganized into CEL not otherwise specified (CEL-NOS) and myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1; CEL-NOS remained a subcategory of MPN, whereas the latter neoplasms were now assigned a new category of their own.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
Gene-disease associations inferred from text-mining the literature.
DisGeNET evidence - LITERATURE