http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#Head http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#assertion http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#provenance http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#pubinfo http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#assertion http://resource.belframework.org/belframework/20131211/namespace/selventa-named-complexes/p85%2Fp110%20PI3Kinase%20Complex http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0043234 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_1 http://purl.obolibrary.org/obo/BFO_0000051 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_2 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_1 http://purl.obolibrary.org/obo/BFO_0000051 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_3 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=1653 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_3 http://purl.obolibrary.org/obo/BFO_0000051 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_4 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0043234 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_4 http://purl.obolibrary.org/obo/RO_0002204 http://resource.belframework.org/belframework/20131211/namespace/selventa-named-complexes/T%20Cell%20Receptor%20Complex http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_5 http://semanticscience.org/resource/SIO_000139 http://resource.belframework.org/belframework/20131211/namespace/selventa-named-complexes/p85%2Fp110%20PI3Kinase%20Complex http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016301 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_6 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/CL_0000898 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_6 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_5 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_1 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#assertion http://www.w3.org/2000/01/rdf-schema#label composite(p(HGNC:CD28),complex(p(SCOMP:"T Cell Receptor Complex"))) -> kin(complex(SCOMP:"p85/p110 PI3Kinase Complex")) http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_8 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_7 http://www.w3.org/ns/prov#value he CD28 signaling pathway primarily involves a small subset of signaling molecules that are also implicated in TCR signal transmission, in particular the phosphoinositide-3 kinase (PI3-K) pathway with downstream activation of AKT [32,33], and activation of TEC protein kinases and of interleukin-2-inducible T-cell kinases [27,34]. AKT activation cooperates with the TCR-induced activation of protein kinase C (PKC)? to activate the NF-?B pathway, which is otherwise only slightly activated by TCR alone. http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_7 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/19007423 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_8 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/19007423 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#_7 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E#pubinfo http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E http://purl.org/dc/terms/created 2014-07-03T14:33:27.995+02:00 http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RA_IDtd66eIowtEp63WdqK2kh-BBq4ENV3pKsGhGL6G9E http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234