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[Remarkably, over 400 distinct point mutations have been so far identified throughout the LMNA gene, which result in the development of at least ten distinct human disorders, collectively known as laminopathies, among which is the premature aging disease Hutchinson-Gilford progeria syndrome (HGPS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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