@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAZkoGqZ3F9rjhFxgn6fAUKJeBV02iA2UNyvT8tfn7Imc> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAZkoGqZ3F9rjhFxgn6fAUKJeBV02iA2UNyvT8tfn7Imc#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix rgd: <http://rgd.mcw.edu/rgdweb/report/gene/main.html?id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
   sub:_1 hasAgent: sub:_2 ;
    a go:0005525 .
  sub:_2 geneProductOf: rgd:619755 ;
    a Protein: .
  sub:_3 hasAgent: sub:_4 ;
    a go:0016301 .
  sub:_4 geneProductOf: rgd:621506 ;
    a Protein: .
  sub:_5 occursIn: obo:CL_0000097 , species:10116 ;
    rdf:object sub:_3 ;
    rdf:predicate belv:increases ;
    rdf:subject sub:_1 ;
    a rdf:Statement .
  sub:assertion rdfs:label "gtp(p(RGD:Rac1)) -> kin(p(RGD:Mapk8))" .
}
sub:provenance {
   beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_7 ;
    pav:version "20131211" .
  sub:_6 prov:value "FceRI stimulation resulted in the activation of Syk, which targeted numerous substrates in mast cells (33). Tyrosine phosphorylation of Vav (a Sykdependent event) was sufficient for the activation of Rac1, but not of Ras. Vav-mediated activation of Rac1 resulted in the induction of JNK1 activity and increased levels of IL-2 and IL-6 mRNAs. Inhibition of Rac1 or JNK1 activity resulted in inhibition of the studied IL-6 response." ;
    prov:wasQuotedFrom pubmed:10395673 .
  sub:_7 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:10395673 ;
    prov:wasDerivedFrom beldoc: , sub:_6 .
}
sub:pubinfo {
   this: dct:created "2014-07-03T14:31:30.962+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}