. . . . . . . . . . . . . . . . . . "a(SCHEM:Tretinoin) -> r(HGNC:TNFSF10)" . "p(HGNC:IRF1) -> (a(SCHEM:Tretinoin) -> r(HGNC:TNFSF10))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "retinoid-induced interferon regulatory factor-1 (IRF-1), a tumor suppressor, is critically required for TRAIL induction by both RA and IFNgamma. Exposure of breast cancer cells to both antitumor agents results in enhanced TRAIL promoter occupancy by IRF-1 and coactivator recruitment, leading to strong histone acetylation and synergistic induction of TRAIL expression." . . "Selventa" . . . . "2014-07-03T14:32:25.309+02:00"^^ . . .