http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#Head http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8 http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#assertion http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8 http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#provenance http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8 http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#pubinfo http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#assertion http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_1 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=12680 http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_2 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/UBERON_0000310 http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_2 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://resource.belframework.org/belframework/20131211/namespace/selventa-legacy-diseases/tumor%20cell%20invasion http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_1 http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#assertion http://www.w3.org/2000/01/rdf-schema#label p(HGNC:VEGFA) -> path(SDIS:"tumor cell invasion") http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_5 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_3 http://purl.org/dc/elements/1.1/identifier Landes Bioscience - Autocrine VEGF Signaling in Breast Cancer http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_3 http://purl.org/dc/elements/1.1/title Landes Bioscience - Autocrine VEGF Signaling in Breast Cancer http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_3 http://purl.org/dc/elements/1.1/type Other http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_4 http://www.w3.org/ns/prov#value VEGFR-1 and VEGFR-2 mRNA was identified in a number of breast cancer cell lines including T-47D, MCF7, MDA-MB-453, and MDA-MB-231, and these cancer cells were shown to respond to VEGF.85,86 VEGF stimulation increased the invasiveness of T-47D cells in the presence of fibronectin.85 ERK-1 and -2 were activated in response to VEGF in T-47D cells; PI3-K and its downstream target Akt were also activated. Since T-47D cells secrete VEGF87 it is likely that an autocrine VEGF loop exists within these cells. PI3-K activation has often been implicated in cellular invasion88 and may be the signalling mechanism in T-47D cells that mediates VEGF-induced cell invasion. http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_4 http://www.w3.org/ns/prov#wasQuotedFrom http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_3 http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_5 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_3 http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#_4 http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8#pubinfo http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8 http://purl.org/dc/terms/created 2014-07-03T14:31:28.235+02:00 http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8 http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAZeMCleTVwGaY2sruX2mfDtQXLjLc0Nbhi5lEfyL0WN8 http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234