@prefix dcterms: . @prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix go: . @prefix RNA: . @prefix hgnc: . @prefix geneProductOf: . @prefix obo: . @prefix occursIn: . @prefix species: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 geneProductOf: hgnc:13672; a RNA: . sub:_2 occursIn: obo:CL_0000232, species:9606; rdf:object sub:_1; rdf:predicate belv:increases; rdf:subject go:0030154; a rdf:Statement . sub:assertion rdfs:label "bp(GOBP:\"cell differentiation\") -> r(HGNC:KLF13)" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_4; pav:version "20131211" . sub:_3 prov:value "FKLF-2 also activated all the other erythroid specific promoters we tested (GATA-1, glycophorin B, ferrochelatase, porphobilinogen deaminase, and 5-aminolevulinate synthase). To test whether FKLF-2 expression changes on induction of erythroid differentiation, K562, HEL, and MEL cells were induced by hemin, delta -ALA, or hemin + HMBA,26,27 and FKLF-2 mRNA was assessed with Northern blotting. As shown in Figure 2C and 2D, induction of erythroid differentiation up-regulated FKLF-2 expression in all 3 cell lines. FKLF-2 thus differs from EKLF and FKLF, which fail to be up-regulated by inducers of erythroid differentiation.1,8"; prov:wasQuotedFrom pubmed:10828046 . sub:_4 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:10828046; prov:wasDerivedFrom beldoc:, sub:_3 . } sub:pubinfo { this: dcterms:created "2014-07-03T14:31:35.586+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }