sub:provenance {
beldoc: dce:description "Approximately 61,000 statements." ;
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title "BEL Framework Large Corpus Document" ;
pav:authoredBy sub:_4 ;
pav:version "20131211" .
sub:_3 prov:value "FKLF-2 also activated all the other erythroid specific promoters we tested (GATA-1, glycophorin B, ferrochelatase, porphobilinogen deaminase, and 5-aminolevulinate synthase). To test whether FKLF-2 expression changes on induction of erythroid differentiation, K562, HEL, and MEL cells were induced by hemin, delta -ALA, or hemin + HMBA,26,27 and FKLF-2 mRNA was assessed with Northern blotting. As shown in Figure 2C and 2D, induction of erythroid differentiation up-regulated FKLF-2 expression in all 3 cell lines. FKLF-2 thus differs from EKLF and FKLF, which fail to be up-regulated by inducers of erythroid differentiation.1,8" ;
prov:wasQuotedFrom pubmed:10828046 .
sub:_4 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:10828046 ;
prov:wasDerivedFrom beldoc: ,
sub:_3 .
}