@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix Protein: . @prefix hgnc: . @prefix geneProductOf: . @prefix RNA: . @prefix obo: . @prefix occursIn: . @prefix species: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 geneProductOf: hgnc:11109; a Protein: . sub:_2 geneProductOf: hgnc:2529; a RNA: . sub:_3 occursIn: obo:CLO_0009727, species:9606; rdf:object sub:_2; rdf:predicate belv:increases; rdf:subject sub:_1; a rdf:Statement . sub:assertion rdfs:label "p(HGNC:SMARCE1) -> r(HGNC:CTSD)" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_5; pav:version "20131211" . sub:_4 prov:value "We then analyzed the effect of BAF57 depletion on the expression of endogenous ER target genes, monitoring mRNA levels by quantitative reverse transcription-PCR (QRT-PCR). The mRNA expression levels of a number of well characterized ER target genes (pS2, cathepsin D, progesterone receptor, BRCA1, BRCA2, and bcl-2) increased in ZR-75-1 cells in response to treatment with 17beta-estradiol (E2) for 24 h, as shown in Fig. 1C. The E2-dependent activation of all of these genes was markedly impaired by transfection with siBAF57 (Fig. 1C), indicating that BAF57 is important for the transcriptional activity of endogenous ER. "; prov:wasQuotedFrom pubmed:16769725 . sub:_5 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:16769725; prov:wasDerivedFrom beldoc:, sub:_4 . } sub:pubinfo { this: dct:created "2014-07-03T14:33:01.212+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }