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[Proposals for change include abandoning the routine use of 'refractory anemia/cytopenia' in the various disease names, including the prognostic significance of gene mutations in MDS, revising the diagnostic criteria for MDS entities with ring sideroblasts based on the detection of SF3B1 mutations, modifying the cytogenetic criteria for MDS with isolated del(5q), reclassifying most cases of the erythroid/myeloid type of acute erythroleukemia, and recognizing the familial link in some cases of MDS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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