. . . . . . . . . . . . . . . . . . "a(CHEBI:lipopolysaccharide) -> bp(GOBP:\"regulation of vascular permeability\")" . "cat(p(MGI:S1pr1)) -| (a(CHEBI:lipopolysaccharide) -> bp(GOBP:\"regulation of vascular permeability\"))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "Extending our prior reports that intravenous (IV) administration of the sphingolipid angiogenic factor, sphingosine 1-phosphate (S1P), attenuates inflammatory lung injury and vascular permeability via ligation of S1PR1, we now determine that direct intratracheal (IT) or intravenous (IV) administration of S1P, or a selective S1PR1 agonist (SEW- 2871), produces highly concentration-dependent barrier-regulatory responses in the murine lung. IT or IV administration of S1P or SEW-2871 at <0.3 mg/kg was protective against LPS-induced murine lung inflammation and permeability," . . "Selventa" . . . . "2014-07-03T14:33:36.167+02:00"^^ . . .