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[Recently mutations in the gene ZFHX1B (SIP1) were shown in patients with `syndromic Hirschsprung disease` with mental retardation (MR) and multiple congenital anomalies (MCA), but it was unclear if Hirschsprung disease is an obligate symptom of these mutations and if the distinct facial phenotype delineated by Mowat et al.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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