. . . . . . . . . . . . "a(SCHEM:\"Oxidized Low Density Lipoprotein\") -> r(HGNC:ABCA1)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "Differentiation of human THP-1 cells into foam cells on treatment with 12-O-tetradecanoylphorbol 13-acetate (PMA) was observed in atherosclerotic lesions. When these THP-1 differentiated cells were subsequently treated with oxidized low density lipoprotein (Ox-LDL), it was observed that ABC1 (a key regulator of the efflux of cholesterol from macrophages) was highly regulated. At the end of fourth day of treatment with Ox-LDL the expression of ABC1 was increased by 10-folds when compared with control. This indicates that Ox-LDL up-regulates ABC1 in differentiated THP-1cells." . . "Selventa" . . . . "2014-07-03T14:31:37.064+02:00"^^ . . .