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a(CHEBI:nicotine) -| p(MGI:Il6)
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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BEL Framework Large Corpus Document
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Intrauterine exposure to nicotine during fetal development in mice resulted in a significant decrease in the number of bone marrow hematopoietic progenitor cells and serum level of IL-6 (a regulator of cell proliferation) via nAChR (282). Nicotine may modulate hematopoiesis by affecting the functions of the bone marrow stromal microenvironment because of reduced expression of CD44, required for the interactions between stromal cells and hematopoietic progenitor cells (expression of CD-44 was reduced in both cells) (151).
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Selventa
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2014-07-03T14:33:11.660+02:00
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