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[Five gout susceptibility loci were identified at the genome-wide significance level (p<5.0�10(-8)), which contained well-known urate transporter genes (ABCG2 and SLC2A9) and additional genes: rs1260326 (p=1.9�10(-12); OR=1.36) of GCKR (a gene for glucose and lipid metabolism), rs2188380 (p=1.6�10(-23); OR=1.75) of MYL2-CUX2 (genes associated with cholesterol and diabetes mellitus) and rs4073582 (p=6.4�10(-9); OR=1.66) of CNIH-2 (a gene for regulation of glutamate signalling).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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