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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAXiCwbVwd6EkopbEz7LO0gku44mWYMI6gEVsvi2qhm1w#_3 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAXiCwbVwd6EkopbEz7LO0gku44mWYMI6gEVsvi2qhm1w#_2 http://www.w3.org/ns/prov#value Furthermore, studies of patients with insulin-secreting tumors suggest that inhibition of hepatic glucose production is the major mechanism whereby insulin lowers plasma glucose in the fasting state. Insulin first acts directly upon adipose tissue to suppress lipolysis and decrease levels of circulating free fatty acids. 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